Breast cancer risk estrogen

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This summary table contains detailed information about research studies. Summary tables are a useful way to look at the science behind many breast cancer guidelines and recommendations. Learn how to read a research table.

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In the Women's Health Initiative, 8, women took combination hormone replacement therapy estrogen and progestin and were followed for an average of 5. The women were evaluated for high risk by the Gail Model and were not found to be at increased risk of developing breast cancer. They had yearly mammograms and breast exams during their follow-up visits.

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Back to Breast cancer in women. The causes of breast cancer are not fully understood, making it difficult to say why one woman may develop breast cancer and another may not. Some of these you cannot do anything about, but there are some you can change.

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Hormones have an important role in our bodies. They play a role in controlling things like growth, fertility and our mood. After the menopause, the ovaries stop producing the female sex hormone oestrogen. So, people may experience menopausal symptoms, like hot flashes and mood changes.

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An international collaboration, using data from more thanwomen with breast cancer from 58 epidemiological studies worldwide, has found that using MHT is associated with an increased risk of breast cancer, and that some increased risk persists for more than a decade after use stops. The findings, published in The Lancetsuggest that all types of MHT, except topical vaginal estrogens, are associated with increased risks of breast cancer, and that the risks are greater for users of estrogen-progestagen hormone therapy than for estrogen-only hormone therapy. For estrogen-progestagen therapy, the risks were greater if the progestagen was included daily rather than intermittently eg, for days per month.

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A sweeping new analysis adds to the evidence that many women who take hormone therapy during menopause are more likely to develop breast cancer — and remain at higher risk of cancer for more than a decade after they stop taking the drugs. The study, published Thursday in the Lancetlooked at data from dozens of studies, including long-term data on more thanwomen who developed breast cancer after menopause. The longer women took the medicine, the more likely they were to develop breast cancer.

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Current or recent past users of hormonal replacement therapy HRT have a higher risk of being diagnosed with breast cancer. Before the link between HRT use and breast cancer risk was established, many postmenopausal women took HRT for many years to ease menopausal symptoms hot flashes, fatigue and to reduce bone loss. Still, many women continue to use HRT to handle bothersome menopausal symptoms.

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Reproductive history and breast cancer risk View all 7 Articles. For decades, it was presumed that the number of years of exposure drove the increased risk, however, recent epidemiological data have shown that early life exposure young menarche has a more significant effect on cancer risk than late menopause. Thus, rather than the overall exposure it seems that the timing of hormone exposure plays a major role in defining breast cancer risk.

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Find information and resources for current and returning patients. Learn about clinical trials at MD Anderson and search our database for open studies. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services.

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For decades, women have used hormone therapy to ease symptoms of menopause, such as hot flashes and sweating. But well-conducted studies have led many doctors to conclude that the risks of MHT often outweigh the benefits. It does not discuss other possible risks of MHT such as heart disease or stroke.

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