Breast cancer recurrence caused by radiation

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The return of breast cancer after a period of remission, referred to as a recurrenceoccurs when cancer cells remain after treatment despite best efforts to eradicate them. These lingering cells can often remain dormant for years and, for reasons not entirely understood, suddenly start to multiply. A recurrence may develop in the same area as the first malignancy, in the opposite breast, or in some other part of the body.

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NCBI Bookshelf. If breast cancer comes back, it is often more frightening than the first time it was diagnosed. But even if it does come back, there are still treatment options.

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The goal of treating early and locally advanced breast cancer is to remove the cancer and keep it from coming back breast cancer recurrence. Most people diagnosed with breast cancer will never have a breast cancer recurrence return of breast cancer. However, everyone who has had breast cancer is at risk of recurrence.

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Radiation therapy was recognized as a potential cause of cancer many years ago. In fact, much of what we know about the possible health effects of radiation therapy has come from studying survivors of atomic bomb blasts in Japan. We also have learned from workers in certain jobs that included radiation exposure, and patients treated with radiation therapy for cancer and other diseases. Most kinds of leukemiaincluding acute myelogenous leukemia AMLchronic myelogenous leukemia CMLand acute lymphoblastic leukemia ALL can be caused by past radiation exposure.

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What is recurrence? Diagnosis 5. Recurrence and prognosis.

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A breast cancer recurrence, or "recurrent breast cancer," is cancer that has come back in the same or opposite breast or chest wall after a period of time when the cancer couldn't be detected. During surgery to remove an original diagnosis of breast cancer lumpectomy or mastectomythe surgeon removes all the cancer that can be seen and felt. But tests for cancer aren't sensitive enough to detect tiny groups of cancer cells that may be left over after surgery.

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Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer.

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What are the symptoms of breast cancer recurrence? What are the chances of breast cancer coming back? Coping with worries about recurrence. After breast-conserving surgery or a mastectomy, with or without reconstruction, be aware of any changes to either side, such as:.

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Although some healthy tissue may be in the treatment area, it generally has the ability to repair itself, unlike cancer cells. In early breast cancer, radiation therapy is used with the aim of getting rid of any malignant or pre-cancerous cells remaining in the breast following partial mastectomy or lumpectomy. This reduces the risk of developing a local recurrence of cancer in the breast in the future.

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This is called recurrent breast cancer and it can appear in the breast after a lumpectomy, the chest area after a mastectomy, or in more distant parts of the body. The likelihood of a recurrent case depends on many factors, including the specific type of cancer including hormone receptors, the stage at diagnosis, and your genetic makeup. A lumpectomy is typically followed by radiation which reduces the risk of cancer returning in the breast.

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